| 1 |  Amgen Inc.AMGN | Biological Products, (No Diagnostic Substances) | $196.87 B |
| 2 |  Gilead Sciences, Inc.GILD | Biological Products, (No Diagnostic Substances) | $166.58 B |
| 3 | Aargenx SEARGX | Biological Products, (No Diagnostic Substances) | $56.26 B |
| 4 | RRevolution Medicines, Inc.RVMD | Biological Products, (No Diagnostic Substances) | $41.02 B |
| 5 |  IQVIA Holdings Inc.IQV | Services-Commercial Physical & Biological Research | $34.91 B |
| 6 |  Moderna, Inc.MRNA | Biological Products, (No Diagnostic Substances) | $30.06 B |
| 7 |  Biogen Inc.BIIB | Biological Products, (No Diagnostic Substances) | $29.50 B |
| 8 |  Incyte CorporationINCY | Services-Commercial Physical & Biological Research | $23.72 B |
| 9 |  BioNTech SEBNTX | Biological Products, (No Diagnostic Substances) | $23.64 B |
| 10 |  Neurocrine Biosciences, Inc.NBIX | Biological Products, (No Diagnostic Substances) | $17.94 B |
| 11 |  Medpace Holdings, Inc.MEDP | Services-Commercial Physical & Biological Research | $15.24 B |
| 12 |  Exelixis, Inc.EXEL | Biological Products, (No Diagnostic Substances) | $14.28 B |
| 13 | IICON Public Limited CompanyICLR | Services-Commercial Physical & Biological Research | $12.79 B |
| 14 |  Bio-Techne CorporationTECH | Biological Products, (No Diagnostic Substances) | $11.14 B |
| 15 |  Charles River Laboratories International, Inc.CRL | Services-Commercial Physical & Biological Research | $11.13 B |
| 16 |  Krystal Biotech, Inc.KRYS | Biological Products, (No Diagnostic Substances) | $10.83 B |
| 17 | AApogee Therapeutics, Inc.APGE | Biological Products, (No Diagnostic Substances) | $9.99 B |
| 18 |  Kymera Therapeutics, Inc.KYMR | Biological Products, (No Diagnostic Substances) | $9.53 B |
| 19 |  Halozyme Therapeutics, Inc.HALO | Biological Products, (No Diagnostic Substances) | $9.39 B |
| 20 | IImmunityBio, Inc.IBRX | Biological Products, (No Diagnostic Substances) | $9.11 B |
| 21 |  Qiagen N.V.QGEN | Biological Products, (No Diagnostic Substances) | $9.04 B |
| 22 | PVaxcyte, Inc.PCVX | Biological Products, (No Diagnostic Substances) | $8.56 B |
| 23 | IImmunovant, Inc.IMVT | Biological Products, (No Diagnostic Substances) | $8.40 B |
| 24 |  Repligen CorporationRGEN | Biological Products, (No Diagnostic Substances) | $8.09 B |
| 25 | SScholar Rock Holding CorporationSRRK | Biological Products, (No Diagnostic Substances) | $6.87 B |
| 26 | AArcellxACLX | Biological Products, (No Diagnostic Substances) | $6.73 B |
| 27 | CCG Oncology, Inc.CGON | Biological Products, (No Diagnostic Substances) | $6.48 B |
| 28 |  Twist Bioscience CorporationTWST | Biological Products, (No Diagnostic Substances) | $5.91 B |
| 29 |  CRISPR Therapeutics AGCRSP | Biological Products, (No Diagnostic Substances) | $5.52 B |
| 30 | DDenali Therapeutics Inc.DNLI | Biological Products, (No Diagnostic Substances) | $4.26 B |
| 31 |  Relay Therapeutics, Inc.RLAY | Biological Products, (No Diagnostic Substances) | $3.92 B |
| 32 |  Beam Therapeutics Inc.BEAM | Biological Products, (No Diagnostic Substances) | $3.76 B |
| 33 |  Adaptive Biotechnologies CorporationADPT | Biological Products, (No Diagnostic Substances) | $3.49 B |
| 34 |  BioCryst Pharmaceuticals, Inc.BCRX | Biological Products, (No Diagnostic Substances) | $2.76 B |
| 35 | TTarsus Pharmaceuticals, Inc.TARS | Biological Products, (No Diagnostic Substances) | $2.74 B |
| 36 | KKodiak Sciences Inc.KOD | Biological Products, (No Diagnostic Substances) | $2.51 B |
| 37 |  Vericel CorporationVCEL | Biological Products, (No Diagnostic Substances) | $2.45 B |
| 38 | AADMA Biologics, Inc.ADMA | Biological Products, (No Diagnostic Substances) | $2.12 B |
| 39 |  Monte Rosa Therapeutics, Inc.GLUE | Biological Products, (No Diagnostic Substances) | $2.07 B |
| 40 |  Recursion Pharmaceuticals, Inc.RXRX | Biological Products, (No Diagnostic Substances) | $2.02 B |
| 41 |  Mesoblast LimitedMESO | Biological Products, (No Diagnostic Substances) | $1.99 B |
| 42 |  Iovance Biotherapeutics, Inc.IOVA | Biological Products, (No Diagnostic Substances) | $1.99 B |
| 43 | TTaysha Gene Therapies, Inc.TSHA | Biological Products, (No Diagnostic Substances) | $1.85 B |
| 44 |  Ethos Technologies Inc.LIFE | Biological Products, (No Diagnostic Substances) | $1.82 B |
| 45 | MMaze Therapeutics, Inc.MAZE | Biological Products, (No Diagnostic Substances) | $1.80 B |
| 46 | AAbsci CorporationABSI | Services-Commercial Physical & Biological Research | $1.79 B |
| 47 | VVir Biotechnology, Inc.VIR | Biological Products, (No Diagnostic Substances) | $1.75 B |
| 48 | CHemab Therapeutics Holdings, Inc.COAG | Biological Products, (No Diagnostic Substances) | $1.74 B |
| 49 | IImmunocore Holdings plcIMCR | Biological Products, (No Diagnostic Substances) | $1.68 B |
| 50 |  Novavax, Inc.NVAX | Biological Products, (No Diagnostic Substances) | $1.54 B |
| 51 | IInhibrx Biosciences, Inc.INBX | Biological Products, (No Diagnostic Substances) | $1.53 B |
| 52 |  Immatics N.V.IMTX | Biological Products, (No Diagnostic Substances) | $1.32 B |
| 53 |  Cullinan Therapeutics, Inc.CGEM | Biological Products, (No Diagnostic Substances) | $1.12 B |
| 54 |  DBV Technologies S.A.DBVT | Biological Products, (No Diagnostic Substances) | $1.11 B |
| 55 | AAlvotechALVO | Biological Products, (No Diagnostic Substances) | $1.04 B |